Overview of Methadone Dosage Administration in Patients Undergoing Methadone Maintenance Therapy

Arifani Siswidiasari; Henni Wati; Yanti Purnama Sari

doi:10.55927/z7sgp975

Authors

Arifani Siswidiasari Kadiri University Author
Henni Wati Kadiri University Author
Yanti Purnama Sari Indonesian Islamic University Author

DOI:

https://doi.org/10.55927/z7sgp975

Keywords:

Dose, Maintenance, Methadone, MMT

Abstract

Narcotics are substances that can cause changes in consciousness and psychoactive effects, while psychotropics are substances that can change a person's feelings, thoughts, or behavior. One of the replacement therapies to prevent intoxication and withdrawal symptoms is methadone maintenance therapy to control dependence and reduce the negative impact of Human Immunodeficiency Virus (HIV)/Acquired Immuno-Deficiency Syndrome (AIDS) transmission. This study aims to obtain an overview of methadone dosage administration in patients undergoing methadone maintenance therapy at the Bangil Community Health Center. This study was conducted retrospectively by collecting medical records of patients undergoing methadone maintenance therapy. The data obtained were 35 patients and analyzed descriptively. The results of demographic data show that the majority of gender is male (33 people), aged 26-35 years 22 people (62.9%), high school education 29 people (82.9%), employed 35 people (100%), and married status 27 people (77.1%). The most common initial dose used was 30-50mg in 23 people (65.7%), the smallest maintenance dose was <60mg in 33 people (94.3%) and the largest maintenance dose was >120mg in 24 people (68.6%)

References

BNN. (2022). Indonesia Drugs Report 2022. Badan Narkotika Nasional.

Farre, M., Mas, A., Torrens, M., Moreno, V., & Cami., J. (2002). Retention rate and illicit opioid use during methadone maintenance interventions: a meta-analysis. 65(3), 283–290. https://doi.org/10.1016/S0376-8716(01)00171-5.

Huissoud T, Rousson V, Dubois-arber F. Methadone treatments in a Swiss Region , 2001 – 2008 : a registrybased analysis. 2012. https://doi.10.1186/1471-244X-12-238

Kemenkes RI. (2013). Peraturan Menteri Kesehatan Republik Indonesia Nomor 57 Tahun 2013 Tentang Pedoman Penyelenggaraan Program Terapi Rumatan Metadon. Kementerian Kesehatan Rebublik Indonesia.

Kemenkes RI. (2009). Undang-Undang Nomor 35 Tahun 2009 tentang Narkotika. Kementerian Kesehatan Rebublik Indonesia.

Megawati, S., & Septia, R. (2024). Gambaran Penggunaan Dosis Metadon Pasien Program Terapi Rumatan Metadon (PTRM) di UPT Puskesmas Cibodasari Tangerang Periode Januari-Desember 2022. Jurnal Farmagazine, XI (1), 59–63. http://dx.doi.org/10.47653/farm.v11i1.746

Siswidiasari, A., Probosiwi, N., Laili, N. F., Ilmi, T., Yuniarto, P. F., Krisnadewi A. A. I., & Hermawatiningsih, O. D. (2024). Factors Affecting the Retention Value of Drug Addict Patients in Methadone Maintenance Therapy. International Journal of Contemporary Sciences, 2(3), 183–190. https://doi.org/10.55927/ijcs.v1i5.8665

Siswidiasari, A., Sapto Agus, T. D., & Hermawatiningsih, O. D. (2024). Pengaruh Penggunaan Dosis Metadon Terhadap Nilai Retensi. Parapemikir : Jurnal Ilmiah Farmasi, 13(2), 216–221. https://doi.org/10.30591/pjif.v13i2.6588

Siswidiasari, A., Wahab, C. S., & Hermawatiningsih, O. D. (2023). Pengaruh Lama Penggunaan Narkotika Dan Psikotropika Terhadap. 12(2), 232–242. https://doi.org/10.30591/pjif.v12i2.4971

Siswidiasari, A., Prayitno Setiadi, A. A., & Nurmayanti, L. (2019). Hubungan antara Karakteristik Pasien dan Terapi terhadap Nilai Retensi di RSJ Menur Surabaya. Jurnal Ilmu Kefarmasian Indonesia, 17(2), 132. https://doi.org/10.35814/jifi.v17i2.535

Wei, X., Wang, L., Wang, X., Li, J., Li, H and Jia, W. (2013) A study of 6-year retention in methadone maintenance treatment among opioid-dependent patients in Xi’an, J. Addict. Med., vol. 7, no. 5, pp. 342–348, Sep. 2013, https://doi.org 10.1097/ADM.0B013E31829DA05B.